中文
EnglishCatalog No : | IPB14033 |
Reactivity: | Human; Mouse; Rat |
Applications: | WB |
Dilution: | WB: 1:500-2000 |
Gene Name: | VPS45 VPS45A VPS45B |
Protein Name: | VPS45 |
Human Gene Id: | 11311 |
Swiss-Prot: | Q9NRW7 |
Formulation: | Liquid in PBS containing 50% glycerol, 05% BSA and 0188% sodium azide |
Source: | Rabbit |
Purification: | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen |
Concentration: | 1 mg/ml |
Storage&Stability: | -20°C/1 year |
Subcellular Location: | Golgi apparatus membrane; Peripheral membrane protein Endosome membrane; Peripheral membrane protein Associated with Golgi:endosomal vesicles and the trans-Golgi network |
MW: | - |
Background: | Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles This gene is a member of the Sec1 domain family, and shows a high degree of sequence similarity to mouse, rat and yeast Vps45 The exact function of this gene is not known, but its high expression in peripheral blood mononuclear cells suggests a role in trafficking proteins, including inflammatory mediators Multiple alternatively spliced transcript variants have been found for this gene |
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