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| Catalog No ： | IPB14025 |
| Reactivity： | Human; Mouse; Rat |
| Applications： | WB |
| Dilution： | WB: 1:500-2000 |
| Gene Name： | VPS33B |
| Protein Name： | VP33B |
| Human Gene Id： | 26276 |
| Swiss-Prot： | Q9H267 |
| Formulation： | Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide |
| Source： | Rabbit |
| Purification： | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen |
| Concentration： | 1 mg/ml |
| Storage&Stability： | -20°C/1 year |
| Subcellular Location： | Late endosome membrane; Peripheral membrane protein; Cytoplasmic side Lysosome membrane; Peripheral membrane protein; Cytoplasmic side Early endosome Cytoplasmic vesicle, clathrin-coated vesicle Recycling endosome Colocalizes in clusters with VIPAS39 at cytoplasmic organelles (PubMed:19109425) Colocalizes with RAB11A and VIPAS39 on recycling endosomes (PubMed:22753090) Colocalizes with AP-3, clathrin, Rab5 and Rab7b (PubMed:21411634) Colocalizes with Mtuberculosis PtpA in the cytosol of tuberculosis-infected macrophages and associates with phagosomes (PubMed:18474358) |
| MW： | 67870 |
| Background： | Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles This gene is a member of the Sec-1 domain family, and encodes the human ortholog of rat Vps33b which is homologous to the yeast class C Vps33 protein The mammalian class C vacuolar protein sorting proteins are predominantly associated with late endosomes:lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome:lysosome pathway Mutations in this gene are associated with arthrogryposis-renal dysfunction-cholestasis syndrome Alternative splicing results in multiple transcript variants [provided by RefSeq, Jan 2014], |
SPECIES
APPLICATION
TITLE
Taizhou Baijia Biotechnology Co., Ltd. is a research and development company Production A biotechnology company whose main business is the sale of antibodies / recombinant proteins and related products. Have strict antibody production Quality inspection and quality control system, products cover the whole field of life science.
A103, Beide vaccine center, Binhe Road, west of Lujia Road
Taizhou pharmaceutical high tech Industrial Development Zone
Taizhou, Jiangsu, P.R.C
+8615216892345
bio100plus@126.com
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