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CCSAP rabbit pAb

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¥1900.00元/format:100ul

目录号:IPB12294

库存:现货
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Catalog No :IPB12294
Reactivity:Human; Mouse;
Applications:WB
Dilution:WB: 1:500-2000
Gene Name:CCSAP C1orf96 CSAP
Protein Name:CCSAP
Human Gene Id:126731
Swiss-Prot:Q6IQ19
Formulation:Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide
Source:Rabbit
Purification:The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
Concentration:1 mg/ml
Storage&Stability:-20°C/1 year
Subcellular Location:Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole Cytoplasm, cytoskeleton, spindle Cytoplasm, cytoskeleton Cytoplasm, cytoskeleton, cilium basal body Cytoplasm, cytoskeleton, cilium axoneme Cell projection, axon Cell projection, cilium Cytoplasm, cytoskeleton, microtubule organizing center, centrosome Localizes to two to four centrioles throughout the cell cycle Localizes to mitotic spindle microtubules during prometaphase and throughout the remainder of mitosis Localizes to cytoskeleton on interphase Localizes at the ciliary transition zone which connects the basal bodies to ciliary microtubules Colocalizes with polyglutamylated tubulin
MW:29700
Background:Plays a role in microtubule (MT) stabilization and this stabilization involves the maintenance of NUMA1 at the spindle poles Colocalizes with polyglutamylated MTs to promote MT stabilization and regulate bipolar spindle formation in mitosis Binding of CCSAP to centrosomes and the spindle around centrosomes during mitosis inhibits MT depolymerization, thereby stabilizing the mitotic spindle May play a role in embryonic development May be required for proper cilia beating (By similarity)

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