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| Catalog No ： | IPB12170 |
| Reactivity： | Human; Mouse; |
| Applications： | WB |
| Dilution： | WB: 1:1000-2000 |
| Gene Name： | ASXL1 KIAA0978 |
| Protein Name： | Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1) |
| Human Gene Id： | 171023 |
| Swiss-Prot： | Q8IXJ9 |
| Formulation： | Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide |
| Source： | Rabbit |
| Purification： | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen |
| Concentration： | 1 mg/ml |
| Storage&Stability： | -20°C/1 year |
| Subcellular Location： | Nucleus |
| MW： | 169510 |
| Background： | Probable Polycomb group (PcG) protein involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors, such as retinoic acid receptors (RARs) and peroxisome proliferator-activated receptor gamma (PPARG) Acts as coactivator of RARA and RXRA through association with NCOA1 Acts as corepressor for PPARG and suppresses its adipocyte differentiation-inducing activity (By similarity) Non-catalytic component of the PR-DUB complex, a complex that specifically mediates deubiquitination of histone H2A monoubiquitinated at 'Lys-119' (H2AK119ub1) Acts as a sensor of N6-methyladenosine methylation on DNA (m6A): recognizes and binds m6A DNA, leading to its ubiquitination and degradation by TRIP12, thereby inactivating the PR-DUB complex and regulating Polycomb silencing |
SPECIES
APPLICATION
TITLE
Taizhou Baijia Biotechnology Co., Ltd. is a research and development company Production A biotechnology company whose main business is the sale of antibodies / recombinant proteins and related products. Have strict antibody production Quality inspection and quality control system, products cover the whole field of life science.
A103, Beide vaccine center, Binhe Road, west of Lujia Road
Taizhou pharmaceutical high tech Industrial Development Zone
Taizhou, Jiangsu, P.R.C
+8615216892345
bio100plus@126.com
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