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EnglishCatalog No : | IPB8026 |
Reactivity: | Human; Mouse; Rat |
Applications: | WB; ELISA |
Dilution: | WB: 1:500-2000 ELISA: 1:5000-20000 |
Gene Name: | MFGE8 |
Protein Name: | Lactadherin (Breast epithelial antigen BA46) (HMFG) (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (SED1) [Cleaved into/ Lactadherin short form; Medin] |
Human Gene Id: | 4240 |
Swiss-Prot: | Q08431 |
Formulation: | Liquid in PBS containing 50% glycerol, and 002% sodium azide |
Source: | Rabbit |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Concentration: | 1 mg/ml |
Storage&Stability: | -20°C/1 year |
Subcellular Location: | Membrane; Peripheral membrane protein Secreted Cytoplasmic vesicle, secretory vesicle, acrosome membrane; Peripheral membrane protein Located in the acrosomal region of zona-pellucida bound sperm |
MW: | - |
Background: | This gene encodes a preproprotein that is proteolytically processed to form multiple protein products The major encoded protein product, lactadherin, is a membrane glycoprotein that promotes phagocytosis of apoptotic cells This protein has also been implicated in wound healing, autoimmune disease, and cancer Lactadherin can be further processed to form a smaller cleavage product, medin, which comprises the major protein component of aortic medial amyloid (AMA) Alternative splicing results in multiple transcript variants |
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