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EnglishCatalog No : | IPB8023 |
Reactivity: | Human; Mouse; Rat |
Applications: | WB; ELISA |
Dilution: | WB: 1:500-2000 ELISA: 1:5000-20000 |
Gene Name: | MEPE |
Protein Name: | Matrix extracellular phosphoglycoprotein (Osteoblast/osteocyte factor 45) (OF45) |
Human Gene Id: | 56955 |
Swiss-Prot: | Q9NQ76 |
Formulation: | Liquid in PBS containing 50% glycerol, and 002% sodium azide |
Source: | Rabbit |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Concentration: | 1 mg/ml |
Storage&Stability: | -20°C/1 year |
Subcellular Location: | Secreted, extracellular space, extracellular matrix |
MW: | - |
Background: | This gene encodes a secreted calcium-binding phosphoprotein that belongs to the small integrin-binding ligand, N-linked glycoprotein (SIBLING) family of proteins Members of this family are components of the extracellular matrix of bone and dentin and regulate bone mineralization Deficiency of a similar protein in mouse results in increased bone mass Mice lacking this gene are resistant to aging-related trabecular bone loss Alternative splicing results in multiple transcript variants |
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