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| Catalog No ： | IPB8022 |
| Reactivity： | Human; Mouse; Rat |
| Applications： | WB; ELISA |
| Dilution： | WB: 1:500-2000 ELISA: 1:5000-20000 |
| Gene Name： | MEP1B |
| Protein Name： | Meprin A subunit beta (EC 342463) (Endopeptidase-2) (Meprin B) (N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta) (PABA peptide hydrolase) (PPH beta) |
| Human Gene Id： | 4225 |
| Swiss-Prot： | Q16820 |
| Formulation： | Liquid in PBS containing 50% glycerol, and 002% sodium azide |
| Source： | Rabbit |
| Purification： | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Concentration： | 1 mg/ml |
| Storage&Stability： | -20°C/1 year |
| Subcellular Location： | Cell membrane; Single-pass type I membrane protein Secreted Homodimers are essentially membrane bound but may also be shed from the surface by ADAM-10 and ADAM-17 |
| MW： | - |
| Background： | Meprins are multidomain zinc metalloproteases that are highly expressed in mammalian kidney and intestinal brush border membranes, and in leukocytes and certain cancer cells They are involved in the hydrolysis of a variety of peptide and protein substrates, and have been implicated in cancer and intestinal inflammation Mature meprins are oligomers of evolutionarily related, but separately encoded alpha and:or beta subunits Homooligomers of alpha subunit are secreted, whereas, oligomers containing the beta subunit are plasma membrane-bound This gene encodes the beta subunit Targeted disruption of this gene in mice affects embryonic viability, renal gene expression profiles, and distribution of the membrane-associated alpha subunit in kidney and intestine |
SPECIES
APPLICATION
TITLE
Taizhou Baijia Biotechnology Co., Ltd. is a research and development company Production A biotechnology company whose main business is the sale of antibodies / recombinant proteins and related products. Have strict antibody production Quality inspection and quality control system, products cover the whole field of life science.
A103, Beide vaccine center, Binhe Road, west of Lujia Road
Taizhou pharmaceutical high tech Industrial Development Zone
Taizhou, Jiangsu, P.R.C
+8615216892345
bio100plus@126.com
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