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EnglishCatalog No : | IPB4265 |
Reactivity: | Human; Mouse; Rat |
Applications: | WB; IHC; IF/ICC; ELISA |
Dilution: | WB: 1:500-1:2000 IHC: 1:50-1:200 IF: 1:50-1:200 ELISA: 1:5000 |
Gene Name: | MADD |
Protein Name: | MAP kinase-activating death domain protein |
Human Gene Id: | 8567 |
Swiss-Prot: | Q8WXG6 |
Formulation: | Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide |
Source: | Rabbit |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Concentration: | 1 mg/ml |
Storage&Stability: | -20°C/1 year |
Subcellular Location: | Cell membrane Cytoplasm Cell projection, axon |
MW: | 183303 |
Background: | This gene encodes a protein that is similar to Maf1, a Saccharomyces cerevisiae protein highly conserved in eukaryotic cells Yeast Maf1 is a negative effector of RNA polymerase III (Pol III) It responds to changes in the cellular environment and represses pol III transcription Biochemical studies identified the initiation factor TFIIIB as a target for Maf1-dependent repression |
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