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MAD2L1BP Polyclonal Antibody

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¥1900.00元/format:100ul

目录号:IPB4264

库存:现货
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Catalog No :IPB4264
Reactivity:Human; Mouse; Rat
Applications:WB; ELISA
Dilution:WB: 1:500-1:2000 ELISA: 1:10000
Gene Name:MAD2L1BP
Protein Name:MAD2L1-binding protein
Human Gene Id:9587
Swiss-Prot:Q15013
Formulation:Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide
Source:Rabbit
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Concentration:1 mg/ml
Storage&Stability:-20°C/1 year
Subcellular Location:Nucleus Cytoplasm, cytoskeleton, spindle During early mitosis, unevenly distributed throughout the nucleoplasm From metaphase to anaphase, concentrated on the spindle
MW:31052
Background:Tumor necrosis factor alpha (TNF-alpha) is a signaling molecule that interacts with one of two receptors on cells targeted for apoptosis The apoptotic signal is transduced inside these cells by cytoplasmic adaptor proteins The protein encoded by this gene is a death domain-containing adaptor protein that interacts with the death domain of TNF-alpha receptor 1 to activate mitogen-activated protein kinase (MAPK) and propagate the apoptotic signal It is membrane-bound and expressed at a higher level in neoplastic cells than in normal cells Several transcript variants encoding different isoforms have been described for this gene

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