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| Catalog No ： | IPB4263 |
| Reactivity： | Human; Mouse; Rat |
| Applications： | WB; IP;ELISA |
| Dilution： | WB: 1:500-1:2000 IP: 1:50 ELISA: 1:5000 |
| Gene Name： | MAD2L1 |
| Protein Name： | Mitotic spindle assembly checkpoint protein MAD2A |
| Human Gene Id： | 4085 |
| Swiss-Prot： | Q13257 |
| Formulation： | Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide |
| Source： | Rabbit |
| Purification： | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Concentration： | 1 mg/ml |
| Storage&Stability： | -20°C/1 year |
| Subcellular Location： | Nucleus Chromosome, centromere, kinetochore Cytoplasm Cytoplasm, cytoskeleton, spindle pole Recruited by MAD1L1 to unattached kinetochores (Probable) Recruited to the nuclear pore complex by TPR during interphase Recruited to kinetochores in late prometaphase after BUB1, CENPF, BUB1B and CENPE Kinetochore association requires the presence of NEK2 Kinetochore association is repressed by UBD Sequestered to the cytoplasm upon interaction with isoform 3 of MAD1L1 (PubMed:19010891) |
| MW： | 23510 |
| Background： | The protein encoded by this gene was identified as a binding protein of the MAD2 mitotic arrest deficient-like 1 (MAD2:MAD2L1) MAD2 is a key component of the spindle checkpoint that delays the onset of anaphase until all the kinetochores are attached to the spindle This protein may interact with the spindle checkpoint and coordinate cell cycle events in late mitosis Alternatively spliced transcript variants encoding distinct isoforms have been observed |
SPECIES
APPLICATION
TITLE
Taizhou Baijia Biotechnology Co., Ltd. is a research and development company Production A biotechnology company whose main business is the sale of antibodies / recombinant proteins and related products. Have strict antibody production Quality inspection and quality control system, products cover the whole field of life science.
A103, Beide vaccine center, Binhe Road, west of Lujia Road
Taizhou pharmaceutical high tech Industrial Development Zone
Taizhou, Jiangsu, P.R.C
+8615216892345
bio100plus@126.com
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