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| Catalog No ： | IPB4262 |
| Reactivity： | Human; Mouse; Rat |
| Applications： | IF/ICC; ELISA |
| Dilution： | IF: 1:50-1:200 ELISA: 1:10000 |
| Gene Name： | MAD1L1 |
| Protein Name： | Mitotic spindle assembly checkpoint protein MAD1 |
| Human Gene Id： | 8379 |
| Swiss-Prot： | Q9Y6D9 |
| Formulation： | Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide |
| Source： | Rabbit |
| Purification： | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Concentration： | 1 mg/ml |
| Storage&Stability： | -20°C/1 year |
| Subcellular Location： | Nucleus Chromosome, centromere, kinetochore Nucleus envelope Cytoplasm, cytoskeleton, microtubule organizing center, centrosome Cytoplasm, cytoskeleton, spindle Cytoplasm, cytoskeleton, spindle pole Co-localizes with TPR at the nucleus envelope during interphase and throughout the cell cycle (PubMed:22351768, PubMed:18981471) From the beginning to the end of mitosis, it is seen to move from a diffusely nuclear distribution to the centrosome, to the spindle midzone and finally to the midbody (PubMed:9546394) Localizes to kinetochores during prometaphase (PubMed:22351768, PubMed:29162720) Does not localize to kinetochores during metaphase (PubMed:29162720) Colocalizes with NEK2 at the kinetochore (PubMed:14978040) Colocalizes with IK at spindle poles during metaphase and anaphase (PubMed:22351768) [Isoform 3]: Cytoplasm |
| MW： | 83067 |
| Background： | MAD2L1 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate MAD2L1 is related to the MAD2L2 gene located on chromosome 1 A MAD2 pseudogene has been mapped to chromosome 14 |
SPECIES
APPLICATION
TITLE
Taizhou Baijia Biotechnology Co., Ltd. is a research and development company Production A biotechnology company whose main business is the sale of antibodies / recombinant proteins and related products. Have strict antibody production Quality inspection and quality control system, products cover the whole field of life science.
A103, Beide vaccine center, Binhe Road, west of Lujia Road
Taizhou pharmaceutical high tech Industrial Development Zone
Taizhou, Jiangsu, P.R.C
+8615216892345
bio100plus@126.com
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