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EnglishCatalog No : | IPB4230 |
Reactivity: | Human; Mouse; Rat |
Applications: | WB; ELISA |
Dilution: | WB: 1:500-2000 ELISA: 1:10000-20000 |
Gene Name: | LHCGR LCGR LGR2 LHRHR |
Protein Name: | Lutropin-choriogonadotropic hormone receptor (LH/CG-R) (Luteinizing hormone receptor) (LHR) (LSH-R) |
Human Gene Id: | 3973 |
Swiss-Prot: | P22888 |
Formulation: | Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide |
Source: | Rabbit |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Concentration: | 1 mg/ml |
Storage&Stability: | -20°C/1 year |
Subcellular Location: | Cell membrane; Multi-pass membrane protein |
MW: | - |
Background: | The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site This protein is thought to play a significant role in the signal transduction of hematopoietic cells It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation This protein might be involved in signaling in some cases of breast cancer Three alternatively spliced transcript variants that encode different isoforms have been described for this gene |
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