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| Catalog No ： | IPB3906 |
| Reactivity： | Human; Mouse; Rat |
| Applications： | WB; ELISA |
| Dilution： | WB: 1:500-1:2000 ELISA: 1:10000 |
| Gene Name： | IL4R |
| Protein Name： | Interleukin-4 receptor subunit alpha |
| Human Gene Id： | 3566 |
| Swiss-Prot： | P24394 |
| Formulation： | Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide |
| Source： | Rabbit |
| Purification： | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Concentration： | 1 mg/ml |
| Storage&Stability： | -20°C/1 year |
| Subcellular Location： | Cell membrane; Single-pass type I membrane protein [Isoform 2]: Secreted |
| MW： | 90750 |
| Background： | This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection Alternate splicing results in multiple transcript variants |
SPECIES
APPLICATION
TITLE
Taizhou Baijia Biotechnology Co., Ltd. is a research and development company Production A biotechnology company whose main business is the sale of antibodies / recombinant proteins and related products. Have strict antibody production Quality inspection and quality control system, products cover the whole field of life science.
A103, Beide vaccine center, Binhe Road, west of Lujia Road
Taizhou pharmaceutical high tech Industrial Development Zone
Taizhou, Jiangsu, P.R.C
+8615216892345
bio100plus@126.com
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