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EnglishCatalog No : | IPB3905 |
Reactivity: | Human; Mouse; Rat |
Applications: | WB; ELISA |
Dilution: | WB: 1:500-1:2000 ELISA: 1:40000 |
Gene Name: | IL4I1 |
Protein Name: | L-amino-acid oxidase |
Human Gene Id: | 259307 |
Swiss-Prot: | Q96RQ9 |
Formulation: | Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide |
Source: | Rabbit |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Concentration: | 1 mg/ml |
Storage&Stability: | -20°C/1 year |
Subcellular Location: | Secreted Lysosome Cytoplasmic vesicle, secretory vesicle, acrosome Secreted at the immunological synapse |
MW: | 62881 |
Background: | This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection Alternate splicing results in multiple transcript variants |
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