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IL-2Rβ Polyclonal Antibody

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¥1900.00元/format:100ul

目录号:IPB3895

库存:现货
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Catalog No :IPB3895
Reactivity:Human; Mouse; Rat
Applications:WB; IF/ICC; ELISA
Dilution:WB: 1:500-1:2000 IF: 1:50-1:200 ELISA: 1:10000
Gene Name:IL2RB
Protein Name:Interleukin-2 receptor subunit beta
Human Gene Id:3560
Swiss-Prot:P14784
Formulation:Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide
Source:Rabbit
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Concentration:1 mg/ml
Storage&Stability:-20°C/1 year
Subcellular Location:Cell membrane; Single-pass type I membrane protein
MW:61117
Background:The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2 The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction The intermediate affinity form consists of an alpha:beta subunit heterodimer, while the high affinity form consists of an alpha:beta:gamma subunit heterotrimer Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2 The protein encoded by this gene represents the beta subunit and is a type I membrane protein The use of alternative promoters results in multiple transcript variants encoding the same protein The protein is primarily expressed in the hematopoietic system

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