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| Catalog No ： | IPB3856 |
| Reactivity： | Human; Mouse; Rat |
| Applications： | WB; IHC; ELISA |
| Dilution： | WB: 1:500-1:2000 IHC-p: 1:100-1:200 ELISA: 1:10000 |
| Gene Name： | IL13RA2 |
| Protein Name： | Interleukin-13 receptor subunit alpha-2 |
| Human Gene Id： | 3598 |
| Swiss-Prot： | Q14627 |
| Formulation： | Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide |
| Source： | Rabbit |
| Purification： | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Concentration： | 1 mg/ml |
| Storage&Stability： | -20°C/1 year |
| Subcellular Location： | Membrane; Single-pass type I membrane protein |
| MW： | 44176 |
| Background： | The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation This cytokine and interleukine 2 share many biological activities They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2 This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6 Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1:BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis Alternatively spliced transcript variants of this gene have been reported |
SPECIES
APPLICATION
TITLE
Taizhou Baijia Biotechnology Co., Ltd. is a research and development company Production A biotechnology company whose main business is the sale of antibodies / recombinant proteins and related products. Have strict antibody production Quality inspection and quality control system, products cover the whole field of life science.
A103, Beide vaccine center, Binhe Road, west of Lujia Road
Taizhou pharmaceutical high tech Industrial Development Zone
Taizhou, Jiangsu, P.R.C
+8615216892345
bio100plus@126.com
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