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EnglishCatalog No : | IPB3690 |
Reactivity: | Human; Mouse; Rat |
Applications: | WB; ELISA |
Dilution: | WB: 1:500-1:2000 ELISA: 1:20000 |
Gene Name: | HNF4A:HNF4G |
Protein Name: | Hepatocyte nuclear factor 4-alpha/Hepatocyte nuclear factor 4-gamma |
Human Gene Id: | 3172 |
Swiss-Prot: | P41235 |
Formulation: | Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide |
Source: | Rabbit |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Concentration: | 1 mg/ml |
Storage&Stability: | -20°C/1 year |
Subcellular Location: | Nucleus |
MW: | 52785 |
Background: | The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes This gene may play a role in development of the liver, kidney, and intestines Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms |
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