中文
EnglishCatalog No : | IPB3681 |
Reactivity: | Human; Mouse; Rat |
Applications: | IHC; IF/ICC; ELISA |
Dilution: | IHC: 1:50-1:200 IF: 1:50-1:200 ELISA: 1:40000 |
Gene Name: | HMGN2 |
Protein Name: | Non-histone chromosomal protein HMG-17 |
Human Gene Id: | 3151 |
Swiss-Prot: | P05204 |
Formulation: | Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide |
Source: | Rabbit |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Concentration: | 1 mg/ml |
Storage&Stability: | -20°C/1 year |
Subcellular Location: | Nucleus Cytoplasm Cytoplasmic enrichment upon phosphorylation |
MW: | 9393 |
Background: | This gene encodes a member of the non-histone chromosomal high mobility group protein family The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination |
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