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EnglishCatalog No : | IPB0350 |
Reactivity: | Human; Mouse; Rat |
Applications: | IF/ICC; WB; IHC-p; ELISA |
Dilution: | IF: 1:50-200 WB: 1:500-1:2000 IHC: 1:50-1:200 ELISA: 1:10000 |
Gene Name: | CEBPB |
Protein Name: | CCAAT/enhancer-binding protein beta |
Human Gene Id: | 1051 |
Swiss-Prot: | P17676 |
Formulation: | Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide |
Source: | Rabbit |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Concentration: | 1 mg/ml |
Storage&Stability: | -20°C/1 year |
Subcellular Location: | Nucleus Cytoplasm Translocates to the nucleus when phosphorylated at Ser-288 In T-cells when sumoylated drawn to pericentric heterochromatin thereby allowing proliferation (By similarity) |
MW: | 36106 |
Background: | This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain The encoded protein functions as a homodimer but can also form heterodimers with CCAAT:enhancer-binding proteins alpha, delta, and gamma Activity of this protein is important in the regulation of genes involved in immune and inflammatory responses, among other processes The use of alternative in-frame AUG start codons results in multiple protein isoforms, each with distinct biological functions |
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