中文
EnglishCatalog No : | IPB0347 |
Reactivity: | Human; Mouse; Rat |
Applications: | WB; IHC-p; ELISA |
Dilution: | WB: 1:500-1:2000 IHC-p: 1:100-1:200 ELISA: 1:20000 |
Gene Name: | BNIP3 |
Protein Name: | BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 |
Human Gene Id: | 664 |
Swiss-Prot: | Q12983 |
Formulation: | Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide |
Source: | Rabbit |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Concentration: | 1 mg/ml |
Storage&Stability: | -20°C/1 year |
Subcellular Location: | Mitochondrion Mitochondrion outer membrane; Single-pass membrane protein Coexpression with the EIB 19-kDa protein results in a shift in NIP3 localization pattern to the nuclear envelope Colocalizes with ACAA2 in the mitochondria Colocalizes with SPATA18 at the mitochondrion outer membrane |
MW: | 21541 |
Background: | This gene is encodes a mitochondrial protein that contains a BH3 domain and acts as a pro-apoptotic factor The encoded protein interacts with anti-apoptotic proteins, including the E1B 19 kDa protein and Bcl2 This gene is silenced in tumors by DNA methylation |
SPECIES
APPLICATION
TITLE