中文
EnglishCatalog No : | IPB0343 |
Reactivity: | Human; Mouse; Rat |
Applications: | WB; ELISA |
Dilution: | WB: 1:500-2000 ELISA: 1:5000-20000 |
Gene Name: | BCL3 BCL4 D19S37 |
Protein Name: | B-cell lymphoma 3 protein (BCL-3) (Proto-oncogene BCL3) |
Human Gene Id: | 602 |
Swiss-Prot: | P20749 |
Formulation: | Liquid in PBS containing 50% glycerol, and 002% sodium azide |
Source: | Rabbit |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Concentration: | 1 mg/ml |
Storage&Stability: | -20°C/1 year |
Subcellular Location: | Nucleus Cytoplasm Cytoplasm, perinuclear region Ubiquitination via 'Lys-63'-linked ubiquitin chains is required for nuclear accumulation |
MW: | - |
Background: | This gene is a proto-oncogene candidate It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B |
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