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Atg4b Polyclonal Antibody

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¥1900.00元/format:100ul

目录号:IPB0335

库存:现货
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Catalog No :IPB0335
Reactivity:Human; Mouse;
Applications:WB; IHC-p; ELISA
Dilution:WB: 1:500-1:2000 IHC: 1:50-1:200 ELISA: 1:20000
Gene Name:ATG4B
Protein Name:Cysteine protease ATG4B
Human Gene Id:23192
Swiss-Prot:Q9Y4P1
Formulation:Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide
Source:Rabbit
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Concentration:1 mg/ml
Storage&Stability:-20°C/1 year
Subcellular Location:Cytoplasm Cytoplasm, cytosol Cytoplasmic vesicle, autophagosome Endoplasmic reticulum Mitochondrion Mainly localizes to the cytoplasm, including cytosol (PubMed:29165041) A samll potion localizes to mitochondria; phosphorylation at Ser-34 promotes localization to mitochondria (PubMed:29165041)
MW:44309
Background:Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed This gene encodes a member of the autophagin protein family The encoded protein is also designated as a member of the C-54 family of cysteine proteases Alternate transcriptional splice variants, encoding different isoforms, have been characterized

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