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EnglishCatalog No : | IPB0332 |
Reactivity: | Human; Mouse; Rat |
Applications: | WB; IHC-p; ELISA |
Dilution: | WB: 1:500-1:2000 IHC: 1:50-1:200 ELISA: 1:40000 |
Gene Name: | ASIC1 |
Protein Name: | Acid-sensing ion channel 1 (ASIC1) (Amiloride-sensitive cation channel 2, neuronal) (Brain sodium channel 2) (BNaC2) |
Human Gene Id: | 41 |
Swiss-Prot: | P78348 |
Formulation: | Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide |
Source: | Rabbit |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Concentration: | 1 mg/ml |
Storage&Stability: | -20°C/1 year |
Subcellular Location: | Cell membrane; Multi-pass membrane protein Localizes in synaptosomes at dendritic synapses of neurons Colocalizes with DLG4 (By similarity) |
MW: | - |
Background: | This gene encodes a member of the acid-sensing ion channel (ASIC) family of proteins, which are part of the degenerin:epithelial sodium channel (DEG:ENaC) superfamily Members of the ASIC family are sensitive to amiloride and function in neurotransmission The encoded proteins function in learning, pain transduction, touch sensation, and development of memory and fear Alternatively spliced transcript variants have been described |
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