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AQP2 Polyclonal Antibody

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¥1900.00元/format:100ul

目录号:IPB0330

库存:现货
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Catalog No :IPB0330
Reactivity:Human; Mouse; Rat; Monkey
Applications:WB; IHC-p; IF/ICC; ELISA
Dilution:WB: 1:500-1:2000 IHC: 1:50-1:200 IF: 1:50-1:200 ELISA: 1:10000
Gene Name:AQP2
Protein Name:Aquaporin-2
Human Gene Id:359
Swiss-Prot:P41181
Formulation:Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide
Source:Rabbit
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Concentration:1 mg/ml
Storage&Stability:-20°C/1 year
Subcellular Location:Apical cell membrane; Multi-pass membrane protein Basolateral cell membrane; Multi-pass membrane protein Cell membrane; Multi-pass membrane protein Cytoplasmic vesicle membrane; Multi-pass membrane protein Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein Shuttles from vesicles to the apical membrane (PubMed:15509592) Vasopressin-regulated phosphorylation is required for translocation to the apical cell membrane (PubMed:15509592) PLEKHA8:FAPP2 is required to transport AQP2 from the TGN to sites where AQP2 is phosphorylated (By similarity)
MW:28837
Background:This gene encodes a water channel protein located in the kidney collecting tubule It belongs to the MIP:aquaporin family, some members of which are clustered together on chromosome 12q13 Mutations in this gene have been linked to autosomal dominant and recessive forms of nephrogenic diabetes insipidus

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