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ANPRA Polyclonal Antibody

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¥1900.00元/format:100ul

目录号:IPB0326

库存:现货
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Catalog No :IPB0326
Reactivity:Human; Mouse; Rat
Applications:WB; ELISA
Dilution:WB: 1:500-2000 ELISA: 1:5000-20000
Gene Name:NPR1 ANPRA
Protein Name:Atrial natriuretic peptide receptor 1 (EC 4612) (Atrial natriuretic peptide receptor type A) (ANP-A) (ANPR-A) (NPR-A) (Guanylate cyclase A) (GC-A)
Human Gene Id:4881
Swiss-Prot:P16066
Formulation:Liquid in PBS containing 50% glycerol, and 002% sodium azide
Source:Rabbit
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Concentration:1 mg/ml
Storage&Stability:-20°C/1 year
Subcellular Location:Membrane; Single-pass type I membrane protein
MW:-
Background:Guanylyl cyclases, catalyzing the production of cGMP from GTP, are classified as soluble and membrane forms (Garbers and Lowe, 1994 [PubMed 7982997]) The membrane guanylyl cyclases, often termed guanylyl cyclases A through F, form a family of cell-surface receptors with a similar topographic structure: an extracellular ligand-binding domain, a single membrane-spanning domain, and an intracellular region that contains a protein kinase-like domain and a cyclase catalytic domain GC-A and GC-B function as receptors for natriuretic peptides; they are also referred to as atrial natriuretic peptide receptor A (NPR1) and type B (NPR2; MIM 108961) Also see NPR3 (MIM 108962), which encodes a protein with only the ligand-binding transmembrane and 37-amino acid cytoplasmic domains NPR1 is a membrane-bound guanylate cyclase that serves as the receptor for both atrial and brain natriuretic peptides

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