中文
EnglishCatalog No : | IPB0319 |
Reactivity: | Human; Mouse; Rat |
Applications: | IHC-p; ELISA |
Dilution: | IHC: 1:100-1:200 ELISA: 1:40000 |
Gene Name: | ADAMTS7 |
Protein Name: | A disintegrin and metalloproteinase with thrombospondin motifs 7 |
Human Gene Id: | 11173 |
Swiss-Prot: | Q9UKP4 |
Formulation: | Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide |
Source: | Rabbit |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Concentration: | 1 mg/ml |
Storage&Stability: | -20°C/1 year |
Subcellular Location: | Secreted, extracellular space, extracellular matrix Also found associated with the external cell surface |
MW: | 109695 |
Background: | The protein encoded by this gene is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family Members of this family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains The encoded preproprotein is proteolytically processed to generate the mature enzyme This enzyme contains two C-terminal TS motifs and may regulate vascular smooth muscle cell (VSMC) migration Mutations in this gene may be associated with susceptibility to coronary artery disease |
SPECIES
APPLICATION
TITLE