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ABCG5 Polyclonal Antibody

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¥1900.00元/format:100ul

目录号:IPB0314

库存:现货
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产品信息

Catalog No :IPB0314
Reactivity:Human; Mouse; Rat
Applications:WB; IF/ICC; ELISA
Dilution:WB: 1:500-1:2000 ELISA: 1:5000 IF: 1:50-1:200
Gene Name:ABCG5
Protein Name:ATP-binding cassette sub-family G member 5 (Sterolin-1)
Human Gene Id:64240
Swiss-Prot:Q9H222
Formulation:Liquid in PBS containing 50% glycerol, and 002% sodium azide
Source:Rabbit
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Concentration:1 mg/ml
Storage&Stability:-20°C/1 year
Subcellular Location:Cell membrane; Multi-pass membrane protein Apical cell membrane; Multi-pass membrane protein
MW:-
Background:The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters ABC proteins transport various molecules across extra- and intra-cellular membranes ABC genes are divided into seven distinct subfamilies (ABC1, MDR:TAP, MRP, ALD, OABP, GCN20, White) This protein is a member of the White subfamily The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols It is expressed in a tissue-specific manner in the liver, colon, and intestine This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG8 Mutations in this gene may contribute to sterol accumulation and atheroschlerosis, and have been observed in patients with sitosterolemia

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