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4E-BP1 Polyclonal Antibody

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¥1900.00元/format:100ul

目录号:IPB0311

库存:现货
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Catalog No :IPB0311
Reactivity:Human; Mouse; Rat
Applications:WB; IHC-p; ELISA
Dilution:WB: 1:500-1:2000 IHC: 1:50-1:200 ELISA: 1:20000
Gene Name:EIF4EBP1
Protein Name:Eukaryotic translation initiation factor 4E-binding protein 1
Human Gene Id:1978
Swiss-Prot:Q13541
Formulation:Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide
Source:Rabbit
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Concentration:1 mg/ml
Storage&Stability:-20°C/1 year
Subcellular Location:nucleoplasm,cytoplasm,cytosol,protein complex,
MW:12449
Background:This gene encodes one member of a family of translation repressor proteins The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs Interaction of this protein with eIF4E inhibits complex assembly and represses translation This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation

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