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EnglishCatalog No : | IPB0308 |
Reactivity: | Human; Mouse; Rat |
Applications: | WB; IHC-p; IF/ICC; ELISA |
Dilution: | WB: 1:500-1:2000 IHC: 1:50-1:200 IF: 1:50-1:200 ELISA: 1:10000 |
Gene Name: | YWHAG |
Protein Name: | 14-3-3 protein gamma |
Human Gene Id: | 7532 |
Swiss-Prot: | P61981 |
Formulation: | Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide |
Source: | Rabbit |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Concentration: | 1 mg/ml |
Storage&Stability: | -20°C/1 year |
Subcellular Location: | Cytoplasm |
MW: | 28303 |
Background: | This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the rat ortholog It is induced by growth factors in human vascular smooth muscle cells, and is also highly expressed in skeletal and heart muscles, suggesting an important role for this protein in muscle tissue It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways |
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