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VE-Cadherin Polyclonal Antibody

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¥1900.00元/format:100ul

目录号:IPB0299

库存:现货
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Catalog No :IPB0299
Reactivity:Human; Mouse;
Applications:WB; IHC-p; ELISA
Dilution:WB: 1:500-1:2000 IHC: 1:50-1:200 ELISA: 1:40000
Gene Name:CDH5
Protein Name:Cadherin-5
Human Gene Id:1003
Swiss-Prot:P33151
Formulation:Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide
Source:Rabbit
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Concentration:1 mg/ml
Storage&Stability:-20°C/1 year
Subcellular Location:Cell junction Cell membrane; Single-pass type I membrane protein Found at cell-cell boundaries and probably at cell-matrix boundaries KRIT1 and CDH5 reciprocally regulate their localization to endothelial cell-cell junctions
MW:87516
Background:This gene encodes a classical cadherin of the cadherin superfamily The encoded preproprotein is proteolytically processed to generate the mature glycoprotein This calcium-dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail Functioning as a classical cadherin by imparting to cells the ability to adhere in a homophilic manner, this protein plays a role in endothelial adherens junction assembly and maintenance This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer

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