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EnglishCatalog No : | IPB0270 |
Reactivity: | Human; Mouse; Rat |
Applications: | WB; IHC-p; IF/ICC |
Dilution: | WB: 1:500-2000 IF: 1:50-1:200 IHC: 1:50-1:200 |
Gene Name: | NOS3 |
Protein Name: | Nitric oxide synthase endothelial |
Human Gene Id: | 4846 |
Swiss-Prot: | P29474 |
Formulation: | Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide |
Source: | Rabbit |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Concentration: | 1 mg/ml |
Storage&Stability: | -20°C/1 year |
Subcellular Location: | Cell membrane Membrane, caveola Cytoplasm, cytoskeleton Golgi apparatus Specifically associates with actin cytoskeleton in the G2 phase of the cell cycle; which is favored by interaction with NOSIP and results in a reduced enzymatic activity |
MW: | 133289 |
Background: | Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities Nitric oxide is synthesized from L-arginine by nitric oxide synthases Variations in this gene are associated with susceptibility to coronary spasm Multiple transcript variants encoding different isoforms have been found for this gene |
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