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COL1A2 Polyclonal Antibody

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¥1900.00元/format:100ul

目录号:IPB0264

库存:现货
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Catalog No :IPB0264
Reactivity:Human; Mouse; Rat
Applications:WB; IHC-p; IF/ICC; ELISA
Dilution:WB: 1:500-2000 IHC: 1:50-1:200 IF: 1:50-1:200 ELISA: 1:10000
Gene Name:COL1A2
Protein Name:Collagen alpha-2(I) chain
Human Gene Id:1278
Swiss-Prot:P08123
Formulation:Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide
Source:Rabbit
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Concentration:1 mg/ml
Storage&Stability:-20°C/1 year
Subcellular Location:Secreted, extracellular space, extracellular matrix
MW:129288
Background:This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene

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