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IkB α Rabbit Polyclonal Antibody

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¥1900.00元/format:100ul

目录号:IPB0223

库存:现货
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Catalog No :IPB0223
Reactivity:Human; Mouse; Rat
Applications:WB; IHC-p
Dilution:WB: 1:500-2000 IHC-p: 1:100-1:200
Gene Name:NFKBIA IKBA MAD3 NFKBI
Protein Name:NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkB-alpha) (IkappaBalpha) (Major histocompatibility complex enhancer-binding protein MAD3)
Human Gene Id:4792
Swiss-Prot:P25963
Formulation:Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide
Source:Rabbit
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Concentration:1 mg/ml
Storage&Stability:-20°C/1 year
Subcellular Location:Cytoplasm Nucleus Shuttles between the nucleus and the cytoplasm by a nuclear localization signal (NLS) and a CRM1-dependent nuclear export
MW:-
Background:This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains The encoded protein interacts with REL dimers to inhibit NF-kappa-B:REL complexes which are involved in inflammatory responses The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease

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