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IGF-IR Polyclonal Antibody

¥1900.00元/format:100ul

目录号:IPB0221

库存:现货
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Catalog No :IPB0221
Reactivity:Human; Mouse; Rat
Applications:IF/ICC; WB; IHC-p; ELISA
Dilution:IF: 1:50-200 WB: 1:500-1:2000 IHC: 1:50-1:200 ELISA: 1:10000
Gene Name:IGF1R
Protein Name:Insulin-like growth factor 1 receptor
Human Gene Id:3480:3643
Swiss-Prot:P08069:P06213
Formulation:Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide
Source:Rabbit
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Concentration:1 mg/ml
Storage&Stability:-20°C/1 year
Subcellular Location:Cell membrane; Single-pass type I membrane protein
MW:154793
Background:This receptor binds insulin-like growth factor with a high affinity It has tyrosine kinase activity The insulin-like growth factor I receptor plays a critical role in transformation events Cleavage of the precursor generates alpha and beta subunits It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene

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