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| Catalog No ： | IPB0194 |
| Reactivity： | Human; Mouse; Rat |
| Applications： | WB; IHC-p; ELISA |
| Dilution： | WB: 1:500-1:2000 IHC: 1:50-1:200 ELISA: 1:20000 |
| Gene Name： | XIAP |
| Protein Name： | E3 ubiquitin-protein ligase XIAP |
| Human Gene Id： | 331 |
| Swiss-Prot： | P98170 |
| Formulation： | Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide |
| Source： | Rabbit |
| Purification： | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Concentration： | 1 mg/ml |
| Storage&Stability： | -20°C/1 year |
| Subcellular Location： | Cytoplasm Nucleus TLE3 promotes its nuclear localization |
| MW： | 56685 |
| Background： | This gene encodes a protein that belongs to a family of apoptotic suppressor proteins Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7 Mutations in this gene are the cause of X-linked lymphoproliferative syndrome Alternate splicing results in multiple transcript variants Pseudogenes of this gene are found on chromosomes 2 and 11 |
SPECIES
APPLICATION
TITLE
Taizhou Baijia Biotechnology Co., Ltd. is a research and development company Production A biotechnology company whose main business is the sale of antibodies / recombinant proteins and related products. Have strict antibody production Quality inspection and quality control system, products cover the whole field of life science.
A103, Beide vaccine center, Binhe Road, west of Lujia Road
Taizhou pharmaceutical high tech Industrial Development Zone
Taizhou, Jiangsu, P.R.C
+8615216892345
bio100plus@126.com
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