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AMPKα1 Polyclonal Antibody

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¥1900.00元/format:100ul

目录号:IPB0185

库存:现货
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Catalog No :IPB0185
Reactivity:Human; Mouse; Rat
Applications:WB; IHC-p; IF/ICC; ELISA
Dilution:WB: 1:500-1:2000 IHC: 1:50-1:200 IF: 1:50-1:200 ELISA: 1:10000
Gene Name:PRKAA1
Protein Name:5'-AMP-activated protein kinase catalytic subunit alpha-1
Human Gene Id:5562
Swiss-Prot:Q13131
Formulation:Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide
Source:Rabbit
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Concentration:1 mg/ml
Storage&Stability:-20°C/1 year
Subcellular Location:Cytoplasm Nucleus In response to stress, recruited by p53:TP53 to specific promoters
MW:62808
Background:The protein encoded by this gene belongs to the ser:thr protein kinase family It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK) AMPK is a cellular energy sensor conserved in all eukaryotic cells The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP:ATP ratio AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways Alternatively spliced transcript variants encoding distinct isoforms have been observed

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