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| Catalog No ： | IPB0184 |
| Reactivity： | Human; Mouse; Rat |
| Applications： | WB; IHC-p; IF/ICC |
| Dilution： | WB: 1:500-2000 IF: 1:50-1:200 IHC: 1:50-1:200 |
| Gene Name： | CAV1 |
| Protein Name： | Caveolin-1 |
| Human Gene Id： | 857 |
| Swiss-Prot： | Q03135 |
| Formulation： | Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide |
| Source： | Rabbit |
| Purification： | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Concentration： | 1 mg/ml |
| Storage&Stability： | -20°C/1 year |
| Subcellular Location： | Golgi apparatus membrane; Peripheral membrane protein Cell membrane; Peripheral membrane protein Membrane, caveola; Peripheral membrane protein Membrane raft Golgi apparatus, trans-Golgi network Colocalized with DPP4 in membrane rafts Potential hairpin-like structure in the membrane Membrane protein of caveolae |
| MW： | 20472 |
| Background： | The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42:44 mitogen-activated kinase cascade Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1 |
SPECIES
APPLICATION
TITLE
Taizhou Baijia Biotechnology Co., Ltd. is a research and development company Production A biotechnology company whose main business is the sale of antibodies / recombinant proteins and related products. Have strict antibody production Quality inspection and quality control system, products cover the whole field of life science.
A103, Beide vaccine center, Binhe Road, west of Lujia Road
Taizhou pharmaceutical high tech Industrial Development Zone
Taizhou, Jiangsu, P.R.C
+8615216892345
bio100plus@126.com
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