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EnglishCatalog No : | IPB0164 |
Reactivity: | Human; Mouse; Rat |
Applications: | IF/ICC; WB; ELISA |
Dilution: | IF: 1:50-200 WB: 1:500-1:2000 ELISA: 1:20000 |
Gene Name: | CD81 |
Protein Name: | CD81 antigen |
Human Gene Id: | 975 |
Swiss-Prot: | P60033 |
Formulation: | Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide |
Source: | Rabbit |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Concentration: | 1 mg/ml |
Storage&Stability: | -20°C/1 year |
Subcellular Location: | Cell membrane; Multi-pass membrane protein Basolateral cell membrane; Multi-pass membrane protein Associates with CLDN1 and the CLDN1-CD81 complex localizes to the basolateral cell membrane |
MW: | 25809 |
Background: | The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility This encoded protein is a cell surface glycoprotein that is known to complex with integrins This protein appears to promote muscle cell fusion and support myotube maintenance Also it may be involved in signal transduction This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies Two transcript variants encoding different isoforms have been found for this gene |
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