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MMP-7 Polyclonal Antibody

¥1900.00元/format:100ul

目录号:IPB0157

库存:现货
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Catalog No :IPB0157
Reactivity:Human; Mouse; Rat; Monkey
Applications:WB; IHC-p; ELISA
Dilution:WB: 1:500-1:2000 IHC: 1:50-1:200 ELISA: 1:40000
Gene Name:MMP7
Protein Name:Matrilysin
Human Gene Id:4316
Swiss-Prot:P09237
Formulation:Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide
Source:Rabbit
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Concentration:1 mg/ml
Storage&Stability:-20°C/1 year
Subcellular Location:Secreted, extracellular space, extracellular matrix
MW:29677
Background:This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs) Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis The encoded preproprotein is proteolytically processed to generate the mature protease This secreted protease breaks down proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal hemopexin domain The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa The gene is part of a cluster of MMP genes on chromosome 11 This gene exhibits elevated expression levels in multiple human cancers

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