中文
EnglishCatalog No : | IPB0150 |
Reactivity: | Human; Mouse; Rat |
Applications: | WB; IHC-p; ELISA |
Dilution: | IHC: 1:100-1:200 WB: 1:500-2000 ELISA: 1:10000-20000 |
Gene Name: | SELE ELAM1 |
Protein Name: | E-Selectin |
Human Gene Id: | 6401 |
Swiss-Prot: | P16581 |
Formulation: | Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide |
Source: | Rabbit |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Concentration: | 1 mg/ml |
Storage&Stability: | -20°C/1 year |
Subcellular Location: | Cell membrane; Single-pass type I membrane protein |
MW: | 66655 |
Background: | The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues These proteins are part of the selectin family of cell adhesion molecules Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis |
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