中文
EnglishCatalog No : | IPB0149 |
Reactivity: | Human; Mouse; Rat |
Applications: | WB; ELISA |
Dilution: | WB: 1:500-2000 ELISA: 1:5000-20000 |
Gene Name: | MT-CO2 COII COXII MTCO2 |
Protein Name: | Cytochrome c oxidase subunit 2 (Cytochrome c oxidase polypeptide II) |
Human Gene Id: | 4513 |
Swiss-Prot: | P00403 |
Formulation: | Liquid in PBS containing 50% glycerol, and 002% sodium azide |
Source: | Rabbit |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Concentration: | 1 mg/ml |
Storage&Stability: | -20°C/1 year |
Subcellular Location: | Mitochondrion inner membrane; Multi-pass membrane protein |
MW: | - |
Background: | cofactor: Copper A,disease: Defects in MT-CO2 are a cause of cytochrome c oxidase deficiency (COX deficiency) [MIM: 220110]; also called mitochondrial complex IV deficiency COX deficiency is a clinically heterogeneous disorder The clinical features are ranging from isolated myopathy to severe multisystem disease, with onset from infancy to adulthood,disease: Defects in MT-CO2 are associated with tumor formation,function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water Subunits 1-3 form the functional core of the enzyme complex Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1,similarity: Belongs to the cytochrome c oxidase subunit 2 family |
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