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p38 Polyclonal Antibody

¥1900.00元/format:100ul

目录号:IPB0124

库存:现货
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Catalog No :IPB0124
Reactivity:Human; Mouse; Rat
Applications:IF/ICC; WB; IHC-p; ELISA
Dilution:IF: 1:50-200 WB: 1:500-1:2000 IHC: 1:50-1:200 ELISA: 1:10000
Gene Name:MAPK14
Protein Name:Mitogen-activated protein kinase 14
Human Gene Id:1432
Swiss-Prot:Q16539
Formulation:Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide
Source:Rabbit
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Concentration:1 mg/ml
Storage&Stability:-20°C/1 year
Subcellular Location:Cytoplasm Nucleus
MW:41293
Background:The protein encoded by this gene is a member of the MAP kinase family MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development This kinase is activated by various environmental stresses and proinflammatory cytokines The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1:TAB1 protein with this kinase The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response Four alternatively spliced transcript variants of this gene encoding

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