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Dnmt3b Polyclonal Antibody

¥1900.00元/format:100ul

目录号:IPB0114

库存:现货
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产品信息

Catalog No :IPB0114
Reactivity:Human; Chicken(testedbyourcustomer)
Applications:WB; IHC-p; IF/ICC; ELISA
Dilution:WB: 1:500-1:2000 IHC: 1:50-1:200 IF: 1:50-1:200 ELISA: 1:20000
Gene Name:DNMT3B
Protein Name:DNA (cytosine-5)-methyltransferase 3B
Human Gene Id:1789
Swiss-Prot:Q9UBC3
Formulation:Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide
Source:Rabbit
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Concentration:1 mg/ml
Storage&Stability:-20°C/1 year
Subcellular Location:Nucleus
MW:95751
Background:CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation Studies in mice have demonstrated that DNA methylation is required for mammalian development This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation The protein localizes primarily to the nucleus and its expression is developmentally regulated Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome Eight alternatively spliced transcript variants have been described The full length sequences of variants 4 and 5 have not been determined

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