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| Catalog No ： | IPB0111 |
| Reactivity： | Human; Mouse; Rat |
| Applications： | WB; IHC-p; IF/ICC; ELISA |
| Dilution： | WB: 1:500-1:2000 IHC: 1:50-1:200 IF: 1:50-1:200 ELISA: 1:10000 |
| Gene Name： | CCNE1 |
| Protein Name： | G1/S-specific cyclin-E1 |
| Human Gene Id： | 898 |
| Swiss-Prot： | P24864 |
| Formulation： | Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide |
| Source： | Rabbit |
| Purification： | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Concentration： | 1 mg/ml |
| Storage&Stability： | -20°C/1 year |
| Subcellular Location： | Nucleus |
| MW： | 47077 |
| Background： | The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle Cyclins function as regulators of CDK kinases Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event This cyclin forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1:S transition This protein accumulates at the G1-S phase boundary and is degraded as cells progress through S phase Overexpression of this gene has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis This protein was found to associate with, and be involved in, the phosphorylation of NPAT protein (nuclear protein mapped to the ATM locus), which participates in |
SPECIES
APPLICATION
TITLE
Taizhou Baijia Biotechnology Co., Ltd. is a research and development company Production A biotechnology company whose main business is the sale of antibodies / recombinant proteins and related products. Have strict antibody production Quality inspection and quality control system, products cover the whole field of life science.
A103, Beide vaccine center, Binhe Road, west of Lujia Road
Taizhou pharmaceutical high tech Industrial Development Zone
Taizhou, Jiangsu, P.R.C
+8615216892345
bio100plus@126.com
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