中文
EnglishCatalog No : | IPB0088 |
Reactivity: | Human; Mouse; Rat |
Applications: | WB; IF/ICC; IHC-p |
Dilution: | WB: 1:1000-2000 IHC: 1:50-1:200 IF: 1:50-1:200 |
Gene Name: | MAP1LC3B |
Protein Name: | Microtubule-associated proteins 1A/1B light chain 3B |
Human Gene Id: | 81631 |
Swiss-Prot: | Q9GZQ8 |
Formulation: | PBS, pH 74, containing 05%BSA, 002% sodium azide as Preservative and 50% Glycerol |
Source: | Rabbit |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Concentration: | - |
Storage&Stability: | -20°C/1 year |
Subcellular Location: | Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor Endomembrane system; Lipid-anchor Mitochondrion membrane; Lipid-anchor Cytoplasm, cytoskeleton Cytoplasmic vesicle LC3-II binds to the autophagic membranes LC3-II localizes with the mitochondrial inner membrane during Parkin-mediated mitophagy (PubMed:28017329) Localizes also to discrete punctae along the ciliary axoneme |
MW: | - |
Background: | The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component |
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