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LC3B Polyclonal Antibody

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¥1900.00元/format:100ul

目录号:IPB0088

库存:现货
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Catalog No :IPB0088
Reactivity:Human; Mouse; Rat
Applications:WB; IF/ICC; IHC-p
Dilution:WB: 1:1000-2000 IHC: 1:50-1:200 IF: 1:50-1:200
Gene Name:MAP1LC3B
Protein Name:Microtubule-associated proteins 1A/1B light chain 3B
Human Gene Id:81631
Swiss-Prot:Q9GZQ8
Formulation:PBS, pH 74, containing 05%BSA, 002% sodium azide as Preservative and 50% Glycerol
Source:Rabbit
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Concentration:-
Storage&Stability:-20°C/1 year
Subcellular Location:Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor Endomembrane system; Lipid-anchor Mitochondrion membrane; Lipid-anchor Cytoplasm, cytoskeleton Cytoplasmic vesicle LC3-II binds to the autophagic membranes LC3-II localizes with the mitochondrial inner membrane during Parkin-mediated mitophagy (PubMed:28017329) Localizes also to discrete punctae along the ciliary axoneme
MW:-
Background:The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component

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