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| Catalog No ： | IPB0087 |
| Reactivity： | Human; Mouse; |
| Applications： | WB; IHC-p; IF/ICC; ELISA |
| Dilution： | WB: 1:500-1:2000 IHC: 1:50-1:200 IF: 1:50-1:200 ELISA: 1:5000 |
| Gene Name： | DDIT3 |
| Protein Name： | DNA damage-inducible transcript 3 protein |
| Human Gene Id： | 1649 |
| Swiss-Prot： | P35638 |
| Formulation： | Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide |
| Source： | Rabbit |
| Purification： | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Concentration： | 1 mg/ml |
| Storage&Stability： | -20°C/1 year |
| Subcellular Location： | Cytoplasm Nucleus Present in the cytoplasm under non-stressed conditions and ER stress leads to its nuclear accumulation |
| MW： | 19175 |
| Background： | This gene encodes a member of the CCAAT:enhancer-binding protein (C:EBP) family of transcription factors The protein functions as a dominant-negative inhibitor by forming heterodimers with other C:EBP members, such as C:EBP and LAP (liver activator protein), and preventing their DNA binding activity The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified |
SPECIES
APPLICATION
TITLE
Taizhou Baijia Biotechnology Co., Ltd. is a research and development company Production A biotechnology company whose main business is the sale of antibodies / recombinant proteins and related products. Have strict antibody production Quality inspection and quality control system, products cover the whole field of life science.
A103, Beide vaccine center, Binhe Road, west of Lujia Road
Taizhou pharmaceutical high tech Industrial Development Zone
Taizhou, Jiangsu, P.R.C
+8615216892345
bio100plus@126.com
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