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| Catalog No ： | IPB0083 |
| Reactivity： | Human; Mouse; Rat |
| Applications： | IF/ICC; IHC-p; ELISA |
| Dilution： | IF: 1:50-200 IHC: 1:50-1:200 ELISA: 1:10000 |
| Gene Name： | VEGFA |
| Protein Name： | Vascular endothelial growth factor A |
| Human Gene Id： | 7422 |
| Swiss-Prot： | P15692 |
| Formulation： | Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide |
| Source： | Rabbit |
| Purification： | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Concentration： | 1 mg/ml |
| Storage&Stability： | -20°C/1 year |
| Subcellular Location： | Secreted VEGF121 is acidic and freely secreted VEGF165 is more basic, has heparin-binding properties and, although a significant proportion remains cell-associated, most is freely secreted VEGF189 is very basic, it is cell-associated after secretion and is bound avidly by heparin and the extracellular matrix, although it may be released as a soluble form by heparin, heparinase or plasmin |
| MW： | 27042 |
| Background： | This gene is a member of the PDGF:VEGF growth factor family It encodes a heparin-binding protein, which exists as a disulfide-linked homodimer This growth factor induces proliferation and migration of vascular endothelial cells, and is essential for both physiological and pathological angiogenesis Disruption of this gene in mice resulted in abnormal embryonic blood vessel formation This gene is upregulated in many known tumors and its expression is correlated with tumor stage and progression Elevated levels of this protein are found in patients with POEMS syndrome, also known as Crow-Fukase syndrome Allelic variants of this gene have been associated with microvascular complications of diabetes 1 (MVCD1) and atherosclerosis Alternatively spliced transcript variants encoding different isoforms have been described |
SPECIES
APPLICATION
TITLE
Taizhou Baijia Biotechnology Co., Ltd. is a research and development company Production A biotechnology company whose main business is the sale of antibodies / recombinant proteins and related products. Have strict antibody production Quality inspection and quality control system, products cover the whole field of life science.
A103, Beide vaccine center, Binhe Road, west of Lujia Road
Taizhou pharmaceutical high tech Industrial Development Zone
Taizhou, Jiangsu, P.R.C
+8615216892345
bio100plus@126.com
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