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EnglishCatalog No : | IPB0057 |
Reactivity: | Human; Mouse; Rat; Monkey |
Applications: | WB; IHC-p; IF/ICC; ELISA |
Dilution: | WB: 1:500-1:2000 IHC: 1:50-1:200 IF: 1:50-1:200 ELISA: 1:20000 |
Gene Name: | HSPA5 |
Protein Name: | 78 kDa glucose-regulated protein |
Human Gene Id: | 3309 |
Swiss-Prot: | P11021 |
Formulation: | Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide |
Source: | Rabbit |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Concentration: | 1 mg/ml |
Storage&Stability: | -20°C/1 year |
Subcellular Location: | Endoplasmic reticulum lumen Melanosome Cytoplasm Cell surface Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:12643545) Localizes to the cell surface of epithelial cells in response to high levels of free iron (PubMed:20484814, PubMed:24355926, PubMed:27159390) |
MW: | 72333 |
Background: | The protein encoded by this gene is a member of the heat shock protein 70 (HSP70) family It is localized in the lumen of the endoplasmic reticulum (ER), and is involved in the folding and assembly of proteins in the ER As this protein interacts with many ER proteins, it may play a key role in monitoring protein transport through the cell |
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