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| Catalog No ： | IPB0054 |
| Reactivity： | Human; Mouse; Rat; Chicken(testedbyourcustomer） |
| Applications： | WB; IHC-p; IF/ICC; ELISA |
| Dilution： | WB: 1:500-1:2000 IHC: 1:50-1:200 IF: 1:50-1:200 ELISA: 1:10000 |
| Gene Name： | MAPK8:9:10 |
| Protein Name： | Mitogen-activated protein kinase 8/9/10 |
| Human Gene Id： | 5599:5601:5602 |
| Swiss-Prot： | P45983:P45984:P53779 |
| Formulation： | Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide |
| Source： | Rabbit |
| Purification： | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Concentration： | 1 mg/ml |
| Storage&Stability： | -20°C/1 year |
| Subcellular Location： | Cytoplasm Nucleus Cell junction, synapse In the cortical neurons, predominantly cytoplasmic and associated with the Golgi apparatus and endosomal fraction Increased neuronal activity increases phosphorylated form at synapses (By similarity) Colocalizes with POU5F1 in the nucleus |
| MW： | 48296/48139/52585 |
| Background： | The protein encoded by this gene is a member of the MAP kinase family MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation |
SPECIES
APPLICATION
TITLE
Taizhou Baijia Biotechnology Co., Ltd. is a research and development company Production A biotechnology company whose main business is the sale of antibodies / recombinant proteins and related products. Have strict antibody production Quality inspection and quality control system, products cover the whole field of life science.
A103, Beide vaccine center, Binhe Road, west of Lujia Road
Taizhou pharmaceutical high tech Industrial Development Zone
Taizhou, Jiangsu, P.R.C
+8615216892345
bio100plus@126.com
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