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TGFβ RII Polyclonal Antibody

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¥1900.00元/format:100ul

目录号:IPB0041

库存:现货
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Catalog No :IPB0041
Reactivity:Human; Mouse;
Applications:WB; IHC-p; ELISA
Dilution:WB: 1:500-1:2000 IHC: 1:50-1:200 ELISA: 1:5000
Gene Name:TGFBR2
Protein Name:TGF-beta receptor type-2
Human Gene Id:7048
Swiss-Prot:P37173
Formulation:Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide
Source:Rabbit
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Concentration:1 mg/ml
Storage&Stability:-20°C/1 year
Subcellular Location:Cell membrane; Single-pass type I membrane protein Membrane raft [Isoform 3]: Secreted
MW:64568
Background:This gene encodes a member of the Ser:Thr protein kinase family and the TGFB receptor subfamily The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta This receptor:ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors Alternatively spliced transcript variants encoding different isoforms have been characterized

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